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Item number: TGM-T21457-100mg

Description: Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases. Carbazeran shows inotropic and chronotropic effects in vivo(EC50 = 100 µM). Target: PDE. Smiles: CCNC(=O)OC1CCN(CC1)c1nncc2cc(OC)c(OC)cc12. References: Manevski N, et al. Aldehyde oxidase...

Keywords:	UK 31557, UK31557, UK 31,557, UK-31,557, UK-31557, UK31,557
CAS	70724-25-3
MW:	360.41 D

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Carbazeran

Item number: Cay26092-1

Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3. It inhibits cAMP hydrolysis (IC50 = 4.1 µM in rabbit heart ventricles) selectively over cGMP hydrolysis (IC50 = 171 µM). It induces positive inotropic (EC50 = 100 µM) and negative chronotropic effects in isolated rabbit papillary muscle and right...

Keywords:	N-ethyl-carbamic acid, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester
Application:	PDE2 / PDE3 inhibitor
CAS	70724-25-3
MW:	360.4 D

From 51.00€ *

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