4 products were found matching "702675-74-9"!
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BX795
Item number: TGM-T1830-100mg
Description: BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than GSK3beta. Target: IkappaB/IKK, Chk, CDK, Autophagy, c-Kit, PDK. Smiles:...
| Application: | PDKP1 inhibitor |
| CAS | 702675-74-9 |
| MW: | 591.47 D |
From 55.00€
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BX-795
Item number: Cay14932-5
BX-795 is a multi-kinase inhibitor that is an ATP-competitive inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1) and TANK-binding kinase 1 (TBK1, IC50s = 6 and 11 nM, respectively). It also inhibits the CAMK family kinases AMPK-related kinase 5 (NUAK1, IC50 = 5 nM) and microtubule affinity-regulating...
| Keywords: | N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
| Application: | PDPK1 inhibitor |
| CAS | 702675-74-9 |
| MW: | 591.5 D |
From 111.00€
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BX-795
Item number: SYN-1026-M001
Soluble in DMSO or ethanol. BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of...
| Keywords: | BX795 |
| Application: | PDPK1 inhibitor |
| CAS | 702675-74-9 |
| MW: | 591,5 D |
From 100.00€
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BX-795
Item number: LKT-B9200.5
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
| Keywords: | BX795 |
| Application: | PDPK1 inhibitor |
| CAS | 702675-74-9 |
| MW: | 591.47 D |
From 146.00€
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