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DNA Base Excision Repair Pathway Inhibitor

Item number: Cay16348-10

Apurinic/apyrimidinic endonuclease-1 (Ape-1) is involved in base excision repair, cleaving the phosphodiester linkage that is 5' to the abasic site to produce a single strand break. DNA base excision repair pathway inhibitor is a cell-permeable inhibitor of Ape-1 (IC50 = 3-11 µM). Although not toxic to cells by...

Keywords:	7-Nitroindole-2-Carboxylic Acid, CRT0044876, NSC 69877, 7-nitro-1H-indole-2-carboxylic acid
Application:	Cell-permeable Ape-1 inhibitor
CAS	6960-45-8
MW:	206.2 D

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