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Item number: Cay20977-10

5,6-dihydro-5-Fluorouracil is an active metabolite of the thymidylate synthase inhibitor prodrug 5-fluorouracil (Cay-14416). It is formed from 5-fluorouracil by dihydropyrimidine dehydrogenase (DPD). 5,6-dihydro-5-Fluorouracil is cytotoxic to HaCaT keratinocytes (IC50 = 13.5 µM). Intravenous administration of...

Keywords:	5-DHFU, 5-Fluoro-5,6-dihydrouracil, 5-Fluorodihydropyrimidine-2,4-dione, 5-Fluorodihydrouracil, 5-FUH2,...
Application:	Apoptosis inducer
CAS	696-06-0
MW:	132.1 D

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