Setomimycin is a pre-anthraquinone originally isolated from S. pseudovenezuelae. It is active against a variety of Gram-positive bacteria, including S. aureus, B. subtilis, B. cereus, and M. smegmatis (MICs = 1.56-3.13 µg/ml). It also reduces tumor growth in a Sarcoma-180 mouse solid tumor model when administered at...

Description: Setomimycin is an antibiotic against Gram positive bacteria, including mycobacteria. Target: Others. Smiles: CC(=O)[C@@H]1C(C)=CC(=O)c2c(O)c3c(O)cccc3c(c12)-c1c2[C@@H](C(C)=O)[C@](C)(O)CC(=O)c2c(O)c2c(O)cccc12. References: Präg A, Grüning BA, Häckh M, Lüdeke S, Wilde M, Luzhetskyy A, Richter M,...