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Item number: TGM-TP2108-1mg

Description: ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-alpha from cell membranes. References: Moss et al (2007) Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for...

CAS	689284-12-6
MW:	415.54 D

1,222.00€ *

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