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Item number: Cay32868-1

BX-430 is a noncompetitive allosteric antagonist of the purinergic P2X4 receptor (IC50s = 0.54 and 1.89 µM for the human and Xenopus receptors, respectively). BX-430 is selective for the human P2X4 receptor over the human P2X1, P2X2, P2X5, P2X3, and P2X7 receptors at 5 µM and over mouse and rat P2X4 receptors at 10...

Keywords:	Blocker of P2X4 Compound 3.0, N-[2,6-dibromo-4-(1-methylethyl)phenyl]-N'-3-pyridinyl-urea
Application:	P2X4 receptor antagonist
CAS	688309-70-8
MW:	413.1 D

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