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Item number: Cay15865-5

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 µM) and conversion of LTA4 to LTB4...

Keywords:	4-[4-(phenylmethyl)phenyl]-2-thiazolamine
Application:	Leukotriene A-4 hydrolase inhibitor
CAS	68729-05-5
MW:	268.4 D

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ARM1

Item number: TGM-T21859-100mg

Description: ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase. Target: Aminopeptidase, Epoxide Hydrolase. Smiles: Nc1nc(cs1)-c1ccc(Cc2ccccc2)cc1. References: El-Naggar MH, et al. Synthesis, docking, cytotoxicity, and...

CAS	68729-05-5
MW:	266.36 D

From 41.00€ *

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