- Search results for 683746-68-1
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2 products were found matching "683746-68-1"!
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Item number: Cay13947-1
JNJ-5207787 is an antagonist of the neuropeptide Y (NPY) receptor Y2 that blocks peptide YY binding (IC50 = 100 nM). It displays 100-fold selectivity for Y2 over other NPY receptors and has minimal effect on a panel of 50 receptors, ion channels, and transporters, except for sodium channel 2. JNJ-5207787 is...
| Keywords: | (2E)-N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide |
| Application: | NPY2R antagonist |
| CAS | 683746-68-1 |
| MW: | 510.7 D |
From 79.00€
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Item number: TGM-T15620-10mg
Description: JNJ-5207787 is a penetrates the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. It is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ-5207787 suppresses the binding of peptide YY with pIC50s of 7.0 and 7.1 for the human Y2 receptor and rat Y2 receptor, respectively....
| Application: | NPY2R antagonist |
| CAS | 683746-68-1 |
| MW: | 510.67 D |
From 150.00€
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