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JNJ-5207787
JNJ-5207787

Item number: Cay13947-1

JNJ-5207787 is an antagonist of the neuropeptide Y (NPY) receptor Y2 that blocks peptide YY binding (IC50 = 100 nM). It displays 100-fold selectivity for Y2 over other NPY receptors and has minimal effect on a panel of 50 receptors, ion channels, and transporters, except for sodium channel 2. JNJ-5207787 is...
Keywords: (2E)-N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide
Application: NPY2R antagonist
CAS 683746-68-1
MW: 510.7 D
From 79.00€ *
Review
JNJ-5207787
JNJ-5207787

Item number: TGM-T15620-10mg

Description: JNJ-5207787 is a penetrates the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. It is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ-5207787 suppresses the binding of peptide YY with pIC50s of 7.0 and 7.1 for the human Y2 receptor and rat Y2 receptor, respectively....
Application: NPY2R antagonist
CAS 683746-68-1
MW: 510.67 D
From 150.00€ *
Review