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Item number: Cay19236-5

CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 µM. It does not affect other NAD+-dependent dehydrogenases, including lactate dehydrogenase and malate dehydrogenase 1. CBR-5884 inhibits the proliferation of...

Keywords:	5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic acid, ethyl ester
Application:	PHGDH inhibitor
CAS	681159-27-3
MW:	336.4 D

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CBR-5884

Item number: TGM-T14884-100mg

Description: CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 µM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of...

Application:	PHGDH inhibitor
CAS	681159-27-3
MW:	336.39 D

From 38.00€ *

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