Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-2-related factor 2 pathway. It inhibits phosphoinositide-dependent kinase 1 (IC50 = 6.6 µM) but not PKC in...

Xanthohumol (XN) is one of the active ingredients from hops (and beer) that shows cancer chemopreventive and estrogenic activities. The chemopreventive activities include anti-initiating potential, modulating the activity of enzymes involved in carcinogen metabolism and detoxification in addition of scavenging...

Description: Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Target: Apoptosis, COX, Acyltransferase, Others, HSV,...

Yellow powder. Soluble in DMSO (10mg/ml) or ethanol (10mg/ml). Chemical. CAS: 6754-58-1. Formula: C21H22O5. MW: 354.40. Xanthohumol is a cell-permeable natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via...