Description: DIDS sodium salt (MDL101114ZA) is a dual inhibitor of the proteins ABCA1 and VDAC1. Target: ABC, VDAC. Smiles: O.[Na+].[Na+].[O-]S(=O)(=O)c1cc(ccc1C=Cc1ccc(cc1S([O-])(=O)=O)N=C=S)N=C=S. References: Tsou CY, et al. Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis....

DIDS is a stilbene sulfonate that inhibits anionic transport. It has been used to inhibit Cl- uptake through plasma membrane-localized Cl- channels in order to study chloride transport. It also effectively inhibits various sodium-coupled bicarbonate transporters.Formal Name:...