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Item number: Cay35662-1

GBR 12783 is a dopamine uptake inhibitor (IC50 = 13 nM in rat striatal synaptosomes). It is selective for inhibition of dopamine uptake over norepinephrine or serotonin (5-HT) uptake (IC50s = 230 and 1,100 nM in rat hypothalamic and striatal synaptosomes, respectively). GBR 12783 (10 mg/kg, i.p.) improves learning...

Keywords:	Lu 2-098, MW-486, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)-piperazine, dihydrochloride
Application:	Dopamine uptake inhibitor
CAS	67469-75-4
MW:	485.5 D

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