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Item number: Cay15324-5

SMER3 is a selective inhibitor of Skp1-Cullin-F-box (SCF)MET30 ubiquitin ligase, an E3 ligase that regulates transcription, cell-cycle control, and immune response. It is a small molecule enhancer of rapamycin (Cay-13346), in that it enhances yeast cell lethality in response to rapamycin. SMER3, at 5 µM, upregulates...

Keywords:	MET30 Antagonist, SCFMET30 Inhibitor, 9H-indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Application:	Skp1-Cullin-F-box (SCF)Met30 ubiquitin ligase inhibitor
CAS	67200-34-4
MW:	224.2 D

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SMER3

Item number: TGM-T23371-100mg

Description: SMER3 is an inhibitor of the Skp1-Cullin-F-box (SCF)(Met30) ubiquitin ligase, a member of the SCF E3-ligase family, which regulates diverse cellular processes including transcription, cell-cycle control and immune response. Target: Ligand for E3 Ligase, Others. Smiles: O=C1c2ccccc2-c2nc3nonc3nc12....

Keywords:	SMER 3
CAS	67200-34-4
MW:	224.18 D

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