Description: 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor, binding to the P-site with an IC50 of 3 µM. Target: AChR, Adrenergic Receptor, Adenylyl cyclase. Smiles: C[C@H]1O[C@H](C[C@@H]1O)n1cnc2c(N)ncnc12. References: Bushfield M, et al. Tissue levels, source, and regulation of...

2',5'-dideoxy Adenosine is a nucleoside analog that is one of the first identified cell-permeable, P-site inhibitors of adenylate cyclase. It inhibits forskolin-induced activation of a cAMP-dependent reporter gene in HEK293 cells with an IC50 value of 33 µM.Formal Name: 2',5'-dideoxy-adenosine. CAS Number:...