3 products were found matching "664993-53-7"!
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JW55
Item number: LKT-J8800.1
TNKS1/2 inhibitor.
| Application: | TNKS1/2 inhibitor |
| CAS | 664993-53-7 |
| MW: | 434.49 D |
From 104.00€
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JW 55
Item number: Cay16260-10
JW 55 is an inhibitor of the PARP domain of tankyrases (TNKS) 1 and 2 (IC50s = 1.9 and 0.83 µM, respectively). By inhibiting TNKS1/2, JW 55 stabilizes Axin2 and increases degradation of beta-catenin, inhibiting the beta-catenin signaling pathway (IC50 = 470 nM). It has been shown to decrease canonical Wnt signaling...
| Keywords: | Tankyrase 1/2 Inhibitor IV,... |
| Application: | Wnt/beta-catenin signaling inhibitor, tankyrase inhibitor |
| CAS | 664993-53-7 |
| MW: | 434.5 D |
From 105.00€
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NEW
JW 55
Item number: TGM-T1807-100mg
Description: JW 55 (JW55) is an effective and selective beta-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). Target: Wnt/beta-catenin, PARP. Smiles: COc1ccc(cc1)C1(CNC(=O)c2ccc(NC(=O)c3ccco3)cc2)CCOCC1. References: Waaler J, et al. A novel...
| Keywords: | JW55 |
| Application: | Wnt/beta-catenin signaling inhibitor, tankyrase inhibitor |
| CAS | 664993-53-7 |
| MW: | 434.48 D |
From 29.00€
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