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2-Acetylphenothiazine
2-Acetylphenothiazine

Item number: Cay19056-10

2-Acetylphenothiazine (2-APT) is a selective, cell-active inhibitor of NADPH oxidase 1 (NOX1) that blocks the generation of reactive oxygen species (ROS) in HT-29 cells with an IC50 value of 0.129 µM. It does not affect xanthine oxidase-dependent or mitochondrial ROS generation. 2-APT prevents ROS-dependent...
Keywords: 2-APT, ML-171, NSC 169669, NSC 57951, 1-(10H-phenothiazin-2-yl)-ethanone
Application: NOX1 inhibitor
CAS 6631-94-3
MW: 241.3 D
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