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Glycine-beta-muricholic Acid
Item number: Cay9003230-10
Glycine-beta-muricholic acid (GbetaMCA) is an intestine-selective antagonist of the farnesoid X receptor (FXR) and the glycine-conjugated form of the murine-specific primary bile acid beta-muricholic acid (Cay-20287). It inhibits expression of the FXR target genes Shp and Fgf15 induced by the FXR ligands...
| Keywords: | Gly-MCA, GbetaMCA, N-[(3alpha,5beta,6beta,7beta)-3,6,7-trihydroxy-24-oxocholan-24-yl]-glycine |
| Application: | FXR antagonist |
| CAS | 66225-78-3 |
| MW: | 465.6 D |
From 174.00€
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Gly-beta-MCA
Item number: TGM-T11426-1mg
Description: Gly-beta-MCA is an orally bioactive, enteroselective and potent inhibitor of the farnesoid X receptor (FXR), a bile acid, used in the study of obesity and diabetes. Target: FXR. Smiles: C[C@H](CCC(=O)NCC(O)=O)C1CCC2C3[C@@H](O)[C@@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C. References: Jiang C, et al....
| CAS | 66225-78-3 |
| MW: | 465.62 D |
188.00€
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