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FK-866
FK-866

Item number: Cay13287-5

FK-866 is a highly specific non-competitive inhibitor of Nampt (Ki = 0.4 nM), causing gradual NAD+ depletion. In HepG2 human liver carcinoma cells, NAD+ depletion by FK-866 directs delayed cell death by apoptosis (IC50 = ~1 nM). In normal human smooth muscle cells, FK-866 causes premature senescence, an effect that...
Keywords: K 22.175, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide
Application: NAMPT inhibitor
CAS 658084-64-1
MW: 391.5 D
From 35.00€ *
Review
FK-866
FK-866

Item number: AG-CR1-0011-M001

Nampt/visfatin inhibitor, Inhibitor of NAD biosynthesis, Inhibits the enzyme/substrate complex and the free enzyme (Ki = 0,4 nM and Ki = 0,3 nM, respectively), Apoptosis inducer, Autophagy inducer, Causes premature senescence, Angiogenesis inhibitor.
Keywords: K 22.175, FK866, APO866, WK175, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide
Application: Nampt/visfatin inhibitor
CAS 658084-64-1
MW: 391,5 D
From 39.00€ *
Review
Daporinad, Free Base (APO866, FK866, K22.175, WK175, CAS 658084-64-1), >99%
Daporinad, Free Base (APO866, FK866, K22.175, WK175, CAS...

Item number: LC-D-5600_10mg

Soluble in DMSO
Keywords: K 22.175, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide
Application: NAMPT inhibitor
CAS 658084-64-1
MW: 391,51 D
From 106.00€ *
Review