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AG-1024
AG-1024

Item number: Cay14833-1

The binding of insulin-like growth factor 1 (IGF-1) to the IGF-1 receptor (IGF-1R) initiates a cascade of reactions that promote cell growth and transformation by activating the PI3K/Akt signaling pathway, inhibiting apoptotic pathways, and mediating mitogenic actions. Overexpression of IGF-1R confers tumorigenic...
Keywords: AGS 200, Tyrphostin AG-1024, 2-[[3-bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile
Application: IGF-1R inhibitor
CAS 65678-07-1
MW: 305.2 D
From 73.00€ *
Review
AG-1024
AG-1024

Item number: LKT-A2400.1

Tyrphostin, IGF-1R inhibitor
Keywords: AG1024 (tyrphostin)
Application: Tyrphostin, IGF-1R inhibitor
CAS 65678-07-1
MW: 305.17 D
From 96.00€ *
Review
AG1024
AG1024

Item number: TGM-T2693-100mg

Description: AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 µM), and is less potent for IR(IC50=57 µM). Target: IGF-1R, Apoptosis. Smiles: CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O. References: Párrizas M, et al. Endocrinology. 1997 Apr,138(4):1427-33.
Keywords: Tyrphostin, AGS 200, Tyrphostin AG 1024
CAS 65678-07-1
MW: 305.17 D
From 33.00€ *
Review