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(-)-Sitagliptin (phosphate)
Item number: Cay13252-50
(-)-Sitagliptin is a potent inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 18 nM). It is selective for DPP-4 over DPP-8 (IC50 = 48 µM) as well as several other peptidases, including DPP-9, DPP-2, and amino peptidase P. (-)-Sitagliptin improves glucose tolerance in insulin-resistant Zucker fatty and high-fat diet...
| Keywords: | (R)-Sitagliptin, INN, MK-431, ONO-5435,... |
| Application: | DPP4 inhibitor |
| CAS | 654671-78-0 |
| MW: | 505.3 D |
From 58.00€
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Sitagliptin phosphate
Item number: TGM-T23358-100mg
Description: Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor. Target: Autophagy, DPP-4. Smiles: N[C@@H](CC(N1Cc2nnc(C(F)(F)F)n2CC1)=O)Cc(c(F)c1)cc(F)c1F.OP(O)(O)=O. References: Thomas L, Eckhardt M, Langkopf E, Tadayyon M, Himmelsbach F, Mark M....
| Keywords: | Januvia, Sitagliptin (phosphate), MK-0431 phosphate |
| CAS | 654671-78-0 |
| MW: | 505.31 D |
From 32.00€
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