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ATN-224
Item number: Cay23553-5
ATN-224 is a choline salt of tetrathiomolybdate and an inhibitor of superoxide dismutase 1 (SOD1, IC50s = 2.91 and 3.51 µM in human and mouse blood cells, respectively, in vitro). ATN-224 reduces the viability of cultured oxidative stress-resistant WEHI7.2 murine thymic lymphoma cells (EC50s = 5-6 nM) and human...
| Keywords: | Bis-Choline Tetrathiomolybdate, 2-hydroxy-N,N,N-trimethyl-ethanaminium, tetrathioxomolybdate |
| Application: | SOD1 inhibitor |
| CAS | 649749-10-0 |
| MW: | 432.5 D |
From 38.00€
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ATN-224
Item number: TGM-T14341-100mg
Description: ATN-224 (Bis(choline)tetrathiomolybdate) inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor. Target: Others. Smiles: S=[Mo]([S-])([S-])=S.OCC[N+](C)(C)C.OCC[N+](C)(C)C....
| Keywords: | Bis(choline)tetrathiomolybdate |
| Application: | Antidote (copper) |
| CAS | 649749-10-0 |
| MW: | 432.56 D |
From 30.00€
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