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7alpha,25-dihydroxy Cholesterol
7alpha,25-dihydroxy Cholesterol

Item number: Cay11032-1

GPR183 (also known as Epstein-Barr virus-induced gene 2) is an orphan G protein-coupled receptor (GPCR) that is highly expressed in spleen and is required for humoral immune responses, including B cell migration and T cell-dependent antibody production. 7alpha,25-dihydroxy Cholesterol (7alpha,25-DHC) is a potent...
Keywords: 7alpha,25-DHC, (3beta,7alpha)-cholest-5-ene-3,7,25-triol
Application: GPR183 agonist
CAS 64907-22-8
MW: 418.7 D
From 89.00€ *
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7alpha,25-Dihydroxycholesterol
7alpha,25-Dihydroxycholesterol

Item number: TGM-T14063-1mg

Description: 7alpha,25-dihydroxycholesterol (7alpha,25-OHC) is a potent and selective agonist, as well as an endogenous ligand, of the orphan GPCR receptor EBI2 (GPR183). It serves as a chemokine directing the migration of B cells, T cells, and dendritic cells and exhibits high potency in activating EBI2 (EC50=140...
Keywords: 7alpha,25-OHC
Application: GPR183 agonist
CAS 64907-22-8
MW: 418.65 D
238.00€ *
Review