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Item number: Cay43245-1

An active metabolite of cholesterol, activates EBI2/GPR183 in a GTPgammaS assay (EC50 = 221 nM) but does not bind to EBI2 in CHO cell membranes expressing the human receptor in a radioligand binding assay (IC50 = 2,632 nM), acts as a cellular chaperone that corrects the localization defect of NPC1I1061T in HEK293...

Keywords:	cholest-5-ene-3beta,7beta,25-triol
Application:	Active cholesterol metabolite
CAS	64907-21-7
MW:	418.66 D

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7beta,25-Dihydroxycholesterol

Item number: TGM-T75515-50mg

Description: 7beta,25-Dihydroxycholesterol, an endogenous metabolite, functions as chemoattractants for immune cells that express EBI2 [1]. Target: Others

CAS	64907-21-7
MW:	418.65 D

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