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Necrostatin-1 Inactive Control
Necrostatin-1 Inactive Control

Item number: Cay21192-50

Necrostatin-1 Inactive Control (Nec-1i) is a demethylated variant of necrostatin-1 (Nec-1, Cay-11658), a RIP1 kinase inhibitor. While both Nec-1 and Nec-1i inhibit the immune regulator indoleamine 2,3-dioxygenase, Nec1i is ~100-fold less effective than Nec-1 in inhibiting RIP1 kinase in vitro and 10-fold less potent...
Keywords: Nec-1i, 5-(1H-indol-3-ylmethyl)-2-thioxo-4-imidazolidinone
Application: Inactive RIPK1 inhibitor control
CAS 64419-92-7
MW: 245.3 D
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Necrostatin-1 (inactive control)
Necrostatin-1 (inactive control)

Item number: TGM-T84727-10mg

Description: Necrostatin-1 (Nec-1) (inactive control), an inactive analog of Necrostatin-1, functions as a potent inhibitor of necroptosis [1]. Target: Others. Smiles: O=C1NC(=S)NC1Cc1c[nH]c2ccccc12
Keywords: Nec-1 (inactive control)
Application: Inactive RIPK1 inhibitor control
CAS 64419-92-7
MW: 245.3 D
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Review