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BMS 605541
BMS 605541

Item number: Cay43119-10

A VEGFR2 inhibitor (IC50 = 23 nM), selective for VEGFR2 over 22 other kinases (IC50s = 400->10,000 nM), inhibits VEGF-induced proliferation in HUVECs (IC50 = 25 nM), decreases tumor volume in an L2987 lung adenocarcinoma mouse xenograft model at 90 or 180 mg/kg per day
Keywords: N-cyclopropyl-2,4-difluoro-5-[[[2-(2-pyridinylamino)-5-thiazolyl]methyl]amino]-benzamide
Application: VEGFR2 inhibitor
CAS 639858-32-5
MW: 401.44 D
From 118.00€ *
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