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Item number: Cay29759-1

Fenobam is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5) that binds to an allosteric site. It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate (Cay-20211) in HEK293 cells expressing the human receptor (IC50 = 58 nM) and inhibits...

Keywords:	N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-urea, monohydrate
Application:	mGluR5 noncompetitive antagonist / inverse agonist
CAS	63540-28-3
MW:	284.7 D

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Fenobam hydrate

Item number: TGM-T68959-10mg

Description: Fenobam hydrate is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5). It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate and inhibits basal activity of mGluR5. Fenobam reduces stress-induced hyperthermia, exhibits...

Application:	Targets metabotropic glutamate receptor 5 (GRM5)
CAS	63540-28-3
MW:	284.7 D

From 106.00€ *

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