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Item number: TGM-T1760-100mg

Description: TBPB, an allosteric M1 mAChR agonist, is an [iso]propyl (2-{4-methoxy-3-[3-(4-methylpiperidin-1-yl)propoxy]phenyl}ethyl)carbamate exhibiting a molar mass of 430.6 g/mol. Target: AChR. Smiles: Cc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O. References: Jones CK, et al. J Neurosci. 2008 Oct...

Application:	Muscarinic acetylcholine receptor M1 agonist
CAS	634616-95-8
MW:	404.55 D

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TBPB

Item number: Cay22943-1

TBPB is an allosteric agonist of M1 muscarinic acetylcholine receptors (mAChRs, EC50 = 158 nM in CHO-K1 cells expressing rat recombinant receptors). It is selective for M1 over M2-5 receptors at concentrations up to 10 µM. TBPB (3 µM) potentiates NMDA-evoked currents in CA1 pyramidal cells. It increases production...

Keywords:	1,3-dihydro-1-[1'-[(2-methylphenyl)methyl][1,4'-bipiperidin]-4-yl]-2H-benzimidazol-2-one
Application:	Muscarinic acetylcholine receptor M1 agonist
CAS	634616-95-8
MW:	404.6 D

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