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Item number: Cay15373-1

Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...

Keywords:	6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine
Application:	IkappaBalpha ubiquitination inhibitor
CAS	62645-28-7
MW:	245.3 D

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Ro 106-9920

Item number: TGM-T23242-10mg

Description: Inhibitor of NF-kappaB activation. Target: Others. Smiles: S(=O)(C1=NN2C(C=C1)=NN=N2)C3=CC=CC=C3

Application:	IkappaBalpha ubiquitination inhibitor
CAS	62645-28-7
MW:	245.26 D

From 168.00€ *

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