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Item number: TGM-T6968-5mg

Description: Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension. Target: Guanylate cyclase. Smiles: COC(=O)N(C)c1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncccc12. References: Schermuly RT, et al. Eur Respir...

Keywords:	BAY 632521
Application:	Targets guanylate cyclase soluble subunit alpha [EC:4.6.1.2] (GUCY1A)
CAS	625115-55-1
MW:	422.42 D

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Riociguat

Item number: Cay9000554-10

Riociguat is a stimulator of soluble guanylate cyclase (sGC)., It stimulates recombinant sGC in a concentration-dependent manner in vitro by up to 73-fold when used at a concentration of 100 µM or by up to 112-fold when used in combination with the nitric oxide (NO) donor DEA NONOate (Cay-82100). It has no effect on...

Keywords:	BAY 63-2521, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbamic...
Application:	Soluble guanylate cyclase activator
CAS	625115-55-1
MW:	422.4 D

From 116.00€ *

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