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Pradefovir mesylate
Pradefovir mesylate

Item number: TGM-T19526-10mg

Description: Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 µM. Target: P450. Smiles: CS(O)(=O)=O.Nc1c2ncn(CCOC[P@@](OCC3)(O[C@@H]3c3cccc(Cl)c3)=O)c2ncn1. References: Lin CC, et al. Metabolic activation of Pradefovir by CYP3A4 and...
Keywords: Pradefovir mesilate, Hepavir B, Remofovir mesylate
Application: Targets Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H (P)
CAS 625095-61-6
MW: 519.9 D
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