2 products were found matching "625095-61-6"!
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Pradefovir (mesylate)
Item number: Cay45047-1
A liver-activated prodrug form of adefovir, it is converted to adefovir diphosphate in the liver in rats at 30 mg/kg. SMILES: O=[P@]1(O[C@H](C2=CC(Cl)=CC=C2)CCO1)COCCN3C4=NC=NC(N)=C4N=C3.CS(O)(=O)=O. InChi Code:...
| Keywords: | MB06866, 9-[2-[[(2R,4S)-4-(3-chlorophenyl)-2-oxido-1,3,2-dioxaphosphorinan-2-yl]methoxy]ethyl]-9H-purin-6-amine,... |
| Application: | Liver-activated Adefovir prodrug, reverse transcriptase inhibitor |
| CAS | 625095-61-6 |
| MW: | 519.89 D |
From 119.00€
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Pradefovir mesylate
Item number: TGM-T19526-10mg
Description: Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 µM. Target: P450. Smiles: CS(O)(=O)=O.Nc1c2ncn(CCOC[P@@](OCC3)(O[C@@H]3c3cccc(Cl)c3)=O)c2ncn1. References: Lin CC, et al. Metabolic activation of Pradefovir by CYP3A4 and...
| Keywords: | Pradefovir mesilate, Hepavir B, Remofovir mesylate |
| Application: | Targets Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H (P) |
| CAS | 625095-61-6 |
| MW: | 519.9 D |
From 131.00€
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