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Item number: Cay45219-1

MEK inhibitor II is an inhibitor of MEK1 (IC50 = 0.38 µM in a cell-free assay). It is selective for MEK1 over ERK1 and Raf1 (IC50s = 82.9 and 34.5 µM, respectively). It is also active against T. cruzi (IC50 = 2.77 µM). SMILES: O=C1C(Cl)=C(N2C(CCC2=O)=O)C(C3=C1C=CC=C3)=O. InChi Code:...

Keywords:	IMDNQ1, 1-(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-2,5-pyrrolidinedione
Application:	MEK1 inhibitor
CAS	623163-52-0
MW:	289.67 D

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