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Item number: Cay14829-1

Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs (ITAMs) of FcRgamma chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibitor is an oxindole compound that potently blocks Syk...

Keywords:	OXSI 2, Spleen Tyrosine Kinase, 2,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2-oxo-1H-indole-5-sulfonamide
Application:	Spleen Tyrosine Kinase inhibitor
CAS	622387-85-3
MW:	353.4 D

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OXSI-2

Item number: TGM-T28281-10mg

Description: OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated events in platelets. Target: Syk. Smiles: C(=C1C=2C(NC1=O)=CC=C(S(N)(=O)=O)C2)C=3C=4C(N(C)C3)=CC=CC4. References: Badolia R,...

Keywords:	Syk Inhibitor, OXSI 2
Application:	Spleen Tyrosine Kinase inhibitor
CAS	622387-85-3
MW:	353.39 D

From 106.00€ *

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