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Vorapaxar
Item number: Cay23119-1
Vorapaxar is an orally bioavailable competitive antagonist of the proteinase-activated receptor (PAR1, Ki = 8.1 nM), also known as the thrombin receptor. It is selective for PAR1 over other PARs, as well as a number of GPCRs, ion channels, and receptors. It inhibits platelet aggregation induced by thrombin...
| Keywords: | N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]fu... |
| Application: | PAR1 competitive antagonist |
| CAS | 618385-01-6 |
| MW: | 492.6 D |
From 85.00€
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Vorapaxar
Item number: TGM-T7013-100mg
Description: Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM). Target: Protease-activated Receptor. Smiles: CCOC(=O)N[C@@H]1CC[C@@H]2[C@H](C[C@@H]3[C@@H]([C@@H](C)OC3=O)[C@H]2\C=C\c2ccc(cn2)-c2cccc(F)c2)C1. References: Tang W, Huang B, Wang J, et...
| Keywords: | MK-5348 , SCH 530348 |
| Application: | Targets coagulation factor II (thrombin) receptor (F2R, PAR1) |
| CAS | 618385-01-6 |
| MW: | 492.58 D |
From 65.00€
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