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Item number: Cay30627-1

Amfenac is an inhibitor of COX-1 and COX-2 (IC50s =15.3 and 20.4 nM, respectively, for the recombinant human enzymes) and the active metabolite of the non-steroidal anti-inflammatory drug (NSAID) nepafenac (Cay-23700). Amfenac (150 nM) reduces the migration of 92.1 uveal melanoma cells, as well as proliferation of...

Keywords:	2-amino-3-benzoyl-benzeneacetic acid, monosodium salt, monohydrate
Application:	COX inhibitor, active nepafenac metabolite
CAS	61618-27-7
MW:	295.3 D

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Amfenac Sodium Hydrate

Item number: TGM-T1720-100mg

Description: Amfenac Sodium Hydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. Target: COX. Smiles: O.[Na+].Nc1c(cccc1CC(=O)[O-])C(=O)c1ccccc1. References: Gamache DA, et al. Inflammation, 2000, 24(4), 357-370.

Keywords:	Amfenac Sodium Monohydrate
Application:	Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1)
CAS	61618-27-7
MW:	295.27 D

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