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Item number: TGM-T15393-100mg

Description: Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (sigma2) receptor ligand (pKi: 8.02). Target: Sigma receptor. Smiles: O=C(CCCc1ccccc1)OCC(COC(=O)CCCc1ccccc1)OC(=O)CCCc1ccccc1. References: Rescifina A, et al. Development of a Sigma-2 Receptor...

Keywords:	HPN-100
Application:	Urea cycle disorder agent, Nitrogen binding agent
CAS	611168-24-2
MW:	530.65 D

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Glycerol Phenylbutyrate

Item number: Cay40832-10

Glycerol phenylbutyrate is a pre-prodrug form of the nitrogen-binding prodrug and chemical chaperone sodium 4-phenylbutyrate (Cay-11323). It is converted by pancreatic lipase in the small intestine to sodium 4-phenylbutyrate, which is subsequently converted into the active metabolite phenylacetate via...

Keywords:	GPB, HPN-100, benzenebutanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester
Application:	Sodium 4-phenylbutyrate pre-prodrug form
CAS	611168-24-2
MW:	530.7 D

From 35.00€ *

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