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Item number: TGM-T4973-100mg

Description: Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of...

Keywords:	1,7-DIMETHYLXANTHINE
CAS	611-59-6
MW:	180.16 D

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Paraxanthine

Item number: Cay21068-10

Paraxanthine is an active metabolite of caffeine (Cay-14118). It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist (Kis = 35 and 22 µM, respectively). In vivo, paraxanthine (30 mg/kg) increases striatal cGMP and...

Keywords:	1,7-Dimethylxanthine, NSC 400018, 3,7-dihydro-1,7-dimethyl-1H-purine-2,6-dione
Application:	Caffeine metabolite
CAS	611-59-6
MW:	180.2 D

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