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RGX-104
RGX-104

Item number: Cay42120-10

An LXRa and LXRß agonist, induces recruitment of an SRC-1 fragment in cell-free FRET-based assays (EC50s = 74 and 25 nM for LXRa and LXRß, respectively), induces cholesterol efflux in RAW 264.7 macrophages (EC50 = 17 nM), increases plasma levels of VLDL, LDL, and triglycerides in hamsters at 10 mg/kg twice per day...
Keywords: Abequolixron, SB-742881,...
Application: LXRa / LXRbeta agonist
CAS 610318-54-2
MW: 596.08 D
From 147.00€ *
Review
RGX-104
RGX-104

Item number: TGM-T7768-100mg

Description: RGX-104 (RGX-104 free Acid) free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR). Target: Liver X Receptor. Smiles: C[C@H](CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F. References: Tavazoie M F , Pollack I , Tanqueco R , et al. LXR/ApoE Activation Restricts...
Keywords: SB 742881 , RGX-104 free Acid
Application: Targets liver X receptor beta (NR1H2, LXRB)
CAS 610318-54-2
MW: 596.08 D
From 33.00€ *
Review