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Pirlindole
Item number: Cay22060-1
A selective and reversible MAO-A inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively), selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively), reverses the depressive-like effects induced by CMS, increases hippocampal cell proliferation,...
| Keywords: | 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole |
| Application: | MAO-A inhibitor |
| CAS | 60762-57-4 |
| MW: | 226.3 D |
79.00€
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Pirlindole
Item number: Cay22060-10
Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects...
| Keywords: | 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole |
| Application: | MAO-A inhibitor |
| CAS | 60762-57-4 |
| MW: | 226.3 D |
From 367.00€
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Pirlindole free base
Item number: TGM-T28422-100mg
Description: Pirlindole is a reversible inhibitor of monoamine oxidase A (RIMA). It is structurally and pharmacologically related to metralindole. Target: Others. Smiles: Cc1ccc2n3CCNC4CCCc(c34)c2c1. References: Macedo A, Leiria E, Filipe A. Pirlindole in the treatment of depression: a meta-analysis. Clin Drug...
| Keywords: | Pirlindole, Pyrazidol |
| Application: | Targets monoamine oxidase [EC:1.4.3.4] (MAO, aofH) |
| CAS | 60762-57-4 |
| MW: | 226.32 D |
From 616.00€
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