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Item number: Cay20937-1

Proxyphylline is a methylxanthine derivative and an adenosine receptor antagonist (Ki = 130 µM). It increases coronary flow in isolated guinea pig perfused heart. Proxyphylline reduces systolic and diastolic blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg twice per day for...

Keywords:	NSC 163343, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione
Application:	ADORA1 antagonist, phosphodiestarase inhibitor
CAS	603-00-9
MW:	238.2 D

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Proxyphylline

Item number: TGM-T5940-1mL

Description: Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator. Target: PDE, Adenosine Receptor. Smiles: C(C(C)O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1. References:...

Keywords:	7-(2-Hydroxypropyl)theophylline
Application:	Targets adenosine receptor A1 (ADORA1)
CAS	603-00-9
MW:	238.24 D

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