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Item number: Cay23361-25

Guvacine is an amino acid found in A. catechu (Betel nut). It competitively inhibits GABA uptake (IC50 = 10 µM, Ki = 14 µM) in rat hippocampal brain slices. In vivo, guvacine, at doses ranging from 50-100 mg/kg, decreases spontaneous activity in mice. Administration of guvacine also decreases tail flick reaction...

Keywords:	1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, monohydrochloride
Application:	Competitive GABA uptake inhibitor
CAS	6027-91-4
MW:	163.6 D

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