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AZD 5438
Item number: Cay21598-10
AZD 5438 is a potent inhibitor of the cyclin-dependent kinases (CDKs) 1, 2, and 9 (IC50s = 16, 6, and 20 nM, respectively). AZD 5438 also inhibits the kinase activity of Cdk5/p25 and glycogen synthase kinase 3beta (GSK3beta) (IC50s = 14 and 17 nM, respectively). AZD 5438 induces cell cycle arrest by inhibiting...
| Keywords: | 4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Application: | Cdk1 / Cdk2 / Cdk9 inhibitor |
| CAS | 602306-29-6 |
| MW: | 371.5 D |
From 133.00€
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AZD-5438
Item number: LKT-A965121.100
| Keywords: | AZD5438, MMV676604, 4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine |
| Application: | Cdk1 / Cdk2 / Cdk9 inhibitor |
| CAS | 602306-29-6 |
| MW: | 371.45 D |
From 134.00€
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AZD-5438
Item number: TGM-T2506-100mg
Description: AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM). Target: CDK. Smiles: CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)S(C)(=O)=O)n1. References: Byth KF, et al. Mol Cancer Ther. 2009, 8(7), 1856-1866.
| Keywords: | AZD5438 |
| Application: | Cdk1 / Cdk2 / Cdk9 inhibitor |
| CAS | 602306-29-6 |
| MW: | 371.46 D |
From 42.00€
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