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Chlormethiazole (hydrochloride)
Chlormethiazole (hydrochloride)

Item number: Cay33437-5

Chlormethiazole is a potentiator of GABAA receptors. It potentiates GABA-induced currents in L-M(TK-) cells expressing alpha1beta1gamma2 or alpha1beta2gamma2 subunit-containing GABAA receptors with EC50 values of 0.8 and 3.4 µM, respectively. Chlormethiazole protects against seizures induced by maximal electroshock...
Keywords: Clomethiazole, 5-(2-chloroethyl)-4-methyl-thiazole, monohydrochloride
Application: GABAA receptors potentiator
CAS 6001-74-7
MW: 198.1 D
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