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Eniluracil
Item number: TGM-T7614-100mg
Description: Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity. Target: Others. Smiles: O=c1[nH]cc(C#C)c(=O)[nH]1. References: Kindler H L , Schilsky R L . Eniluracil:...
| Keywords: | 5-Ethynyluracil, GW776C85 |
| Application: | Targets dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] (DPYD) |
| CAS | 59989-18-3 |
| MW: | 136.11 D |
From 40.00€
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Eniluracil
Item number: Cay34251-25
Eniluracil is an irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD, Ki = 1.6 µM), the rate-determining enzyme in the catabolism of pyrimidines, including 5-fluorouracil (Cay-14416). It inhibits liver DPD and elevates plasma pyrimidine levels in rats (ED50s = 1.8 and 10 µg/kg, respectively). Eniluracil...
| Keywords: | 5-Ethynyluracil, 776C85, NSC 687296, 5-ethynyl-2,4(1H,3H)-pyrimidinedione |
| Application: | Irreversible DPYD inhibitor |
| CAS | 59989-18-3 |
| MW: | 136.1 D |
From 59.00€
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