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Vicriviroc (maleate)
Item number: Cay28453-10
Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 µM). Vicriviroc decreases chemotaxis induced by chemokine (C-C...
| Keywords: | SCH 417690,... |
| Application: | CCR5 antagonist, antiviral |
| CAS | 599179-03-0 |
| MW: | 649.7 D |
From 128.00€
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Vicriviroc maleate
Item number: TGM-T3435-100mg
Description: Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1. Target: HIV Protease, CCR. Smiles:...
| Keywords: | SCH-417690 (maleate), SCH-D (maleate) |
| Application: | Targets C-C chemokine receptor type 5 (CCR5, CD195) |
| CAS | 599179-03-0 |
| MW: | 649.7 D |
From 34.00€
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