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Item number: TGM-T2097-5mg

Description: C-7280948 is a PRMT1 inhibitor. Target: Histone Methyltransferase. Smiles: Nc1ccc(cc1)S(=O)(=O)NCCc1ccccc1. References: Bissinger EM, et al. Bioorg Med Chem. 2011 Jun 15,19(12):3717-3731.

Keywords:	C7280948
CAS	587850-67-7
MW:	276.35 D

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C-7280948

Item number: Cay21601-1

C-7280948 is a protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 12.8 µM, in vitro). PRMT1 enzymes transfer a methyl group from S-adenosylmethionine to arginine residues on histones, which leads to transcription. PRMT1 is essential for mixed lineage leukemia oncogenic transformation and thus its...

Keywords:	4-amino-N-(2-phenylethyl)-benzenesulfonamide
Application:	PRMT1 inhibitor
CAS	587850-67-7
MW:	276.4 D

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