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Sorafenib N-oxide
Item number: Cay27830-1
Sorafenib N-oxide is an active metabolite of sorafenib (BAY 43-9006, Cay-10009644), an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD, Kd = 70 nM) and inhibits proliferation of MV4-11 acute myeloid leukemia...
| Keywords: | BAY 67-3472, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide,... |
| Application: | Active metabolite |
| CAS | 583840-03-3 |
| MW: | 480.8 D |
From 187.00€
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Sorafenib N-oxide
Item number: TGM-T36681-1mg
Description: Sorafenib N-oxide is an active metabolite of sorafenib , an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD, Kd = 70 nM) and inhibits proliferation of MV4-11 acute myeloid leukemia (AML) cells...
| CAS | 583840-03-3 |
| MW: | 480.83 D |
From 279.00€
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