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Item number: Cay19168-5

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. BMS-265246 is a cell-permeable inhibitor of Cdk1/cyclin B and Cdk2/cyclin E (IC50s = 6 and 9 nM, respectively). It less potently inhibits Cdk4/cyclin D (IC50 = 0.23 µM). BMS-265246...

Keywords:	(4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-methanone
Application:	Cell-permeable Cdk1/cyclin B & Cdk2/cyclin E inhibitor
CAS	582315-72-8
MW:	345.3 D

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BMS-265246

Item number: TGM-T2679-100mg

Description: BMS-265246 is a potent and selective CDK1/2 inhibitor. Its chemical name is (4-[R-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1H-indol-1-yl]-1H-pyrazolo[3,4-d] pyrimidine-6-amine), and it functions by targeting CDK1 and CDK2 to potentially disrupt cell cycle progression. Target: Angiotensin-converting Enzyme...

Keywords:	BMS265246
Application:	Cell-permeable Cdk1/cyclin B & Cdk2/cyclin E inhibitor
CAS	582315-72-8
MW:	345.34 D

From 30.00€ *

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