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A 425619
A 425619

Item number: TGM-T8562-100mg

Description: A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist. Target: TRP/TRPV Channel. Smiles: N(C(NCC1=CC=C(C(F)(F)F)C=C1)=O)C=2C3=C(C=CC2)C=NC=C3. References: Chakrabarti S , Pattison L A , Singhal K , et al. Acute inflammation sensitizes knee-innervating sensory...
Keywords: 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA
CAS 581809-67-8
MW: 345.32 D
From 76.00€ *
Review
A-425619
A-425619

Item number: Cay42117-10

A TRPV1 antagonist, selective for TRPV1 over a panel of 83 receptors, enzymes, transporters, and ion channels at 10 µM, inhibits capsaicin-, NADA-, anandamide-, or acid-induced increases in intracellular calcium in HEK293 cells expressing human TRPV1 (IC50s = 5, 4, 3, and 2 nM, respectively), increases core body...
Keywords: N-5-isoquinolinyl-N'-[[4-(trifluoromethyl)phenyl]methyl]-urea
Application: TRPV1 antagonist
CAS 581809-67-8
MW: 345.3 D
From 208.00€ *
Review