3 products were found matching "58131-57-0"!
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NSC-207895
Item number: LKT-N7209.1
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Keywords: | NSC207895 |
| Application: | MDMX inhibitor |
| CAS | 58131-57-0 |
| MW: | 279.25 D |
From 144.00€
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NSC 207895
Item number: Cay27949-1
NSC 207895 is an inhibitor of the p53-binding protein MDMX. It decreases MDMX promoter activity in a reporter assay using HT-1080 cells in a concentration-dependent manner. NSC 207895 (5 µmol/L) decreases the expression and protein levels of MDMX and increases the expression of the p53 target gene CDKN1 (p21) in...
| Keywords: | NSC 179940, XI-006, 4-(4-methyl-1-piperazinyl)-7-nitro-2,1,3-benzoxadiazole, 3-oxide |
| Application: | MDM4 inhibitor |
| CAS | 58131-57-0 |
| MW: | 279.3 D |
From 139.00€
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XI-006
Item number: TGM-T6610-100mg
Description: XI-006 (XI-006) suppresses MDMX with IC50 of 2.5 µM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase. Target: p53, Mdm2. Smiles: CN1CCN(CC1)c1ccc([N+]([O-])=O)c2no[n+]([O-])c12. References: Wang H, et al. Mol Cancer Ther, 2011, 10(1), 69-79.
| Keywords: | NSC 207895 |
| Application: | MDM4 inhibitor |
| CAS | 58131-57-0 |
| MW: | 279.25 D |
From 48.00€
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